Numata Publications

　　 Publications:

2008
(56) Hierarchical carbon nanotube assemblies created by sugar-boric or boronic acid interactions, S. Tamesue, M. Numata, K. Kaneko,T. D. James, and Seiji Shinkai, Chem. Commun., in press.
(55) Immobilization of Polythiophene Chirality Induced by a Helix-Forming b-1,3-Glucan Polysaccharide (Schizophyllan) through Sol-Gel Reaction, S. Haraguchi, M. Numata, K. Kaneko, and S. Shinkai, Bull. Chem. Soc. Jpn., 8, 1002 (2008).
(54) Creation of Hierarchical Carbon Nanotube Assemblies through Alternative Packing of Complementary Semi-Artificial b-1,3-Glucan/Carbon Nanotube Composites, M. Numata, K. Sugikawa, K. Kaneko, and S. Shinkai, Chem. Eur. J., 14, 2398 (2008).
(53) Creation of polynucleotide-assisted molecular assemblies in organic solvents:general strategy toward the creation of artificial DNA-like nanoarchitectures , M. Numata, K. Sugiyasu, T. Kishida, S. Haraguchi, N. Fujita, S.-M. Park, Y.-J. Yun, B.-H. Kim, and S. Shinkai, Org. Biomol. Chem., 6, 712 (2008).
2007
(52) Carbohydrate-appended curdlans as a new family of glycoclusters with binding properties both for a polynucleotide and lectins, T. Hasegawa, M. Numata, S. Okumura, T. Kimura, K. Sakurai, and S. Shinkai, Org. Biomol. Chem., 5, 2404 (2007).
(51) b-1,3-Glucan Schizophyllan Can Act as a One-dimensional Host to Arrange Icosahedral Carboranes, M. Numata, S. Tamesue, T. Nagasaki, K. Sakurai, and S. Shinkai, Chem. Lett., 36, 668 (2007).
(50) Controlled Stability of the Triple-Stranded Helical Structure of a b-1,3-Glucan with a Chromophoric Aromatic Moiety at a Peripheral Position, M. Ikeda, S. Haraguchi, M. Numata, and S. Shinkai, Chem. Asian J., 2, 1290 (2007).
(49) Instantaneous Inclusion of a Polynucleotide and Hydrophobic
Guest Molecules into a Helical Core of Cationic b-1,3-Glucan Polysaccharide, M. Ikeda, T. Hasegawa, M. Numata, K. Sugikawa, K. Sakurai, M. Fujiki, and S. Shinkai, J. Am. Chem. Soc., 129, 3979 (2007).
(48) New approach to preparing one-dimensional Au nanowires utilizing a
helical structure constructed by schizophyllan, A.-H. Bae, M. Numata, S. Yamada, and S. Shinkai, New. J. Chem., 31, 618 (2007).
(47) Complex formation between cationic b-1,3-glucan and hetero-sequence
oligodeoxynucleotide and its delivery into macrophage-like cells to induce
cytokine secretion, M. Ikeda, J. Minari, N. Shimada, M. Numata, K. Sakurai, and S. Shinkai, Org. Biomol. Chem., 5, 2219 (2007).
(46) Molecular assemblies as templates toward the creation of functional superstructures,
K. Sada, M. Takeuchi, N. Fujita, M. Numata, and S. Shinkai,Chem. Soc. Rev., 36, 415 (2007).
(45) beta-1,3-glucan (schizophyllan) can act as a one-dimensional host for creating chirally twisted poly(p-phenylene ethynylene), M. Numata, T. Fujisawa, C. Li, S. Haraguchi, M. Ikeda, K. Sakurai, and S. Shinkai, Supramol. Chem., 19, 107 (2007).
2006
(44) beta-1,3-Glucan Polysaccharide (Schizophyllan) Acts as a One-Dimensional Host for Creating Supramolecular Dye Assemblies, M Numata, Shingo Tamesue, Tomohisa Fujisawa, Shuichi Haraguchi, Teruaki Hasegawa, Ah-Hyun Bae, Chun Li, Kazuo Sakurai, and Seiji Shinkai, Org. Lett., 8, 5533 (2006).
(43) Unexpected chiroptical inversion observed for supramolecular complexes formed between an achiral polythiophene and ATP, C. Li, M. Numata, M. Takeuchi, S. Shinkai. Chem. Asian, J., 1, 95 (2006).
(42) Galactose-PEG dual conjugation of beta-1,3-D-glucan schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake, R. Karinaga, T. Anada, J. Minari, M. Mizu, K. Koumoto, J. Jukuda, K. Nakazawa, T. Hasegawa, M. Numata, S. Shinkai, K. Sakurai, Biomaterials, 27, 1626 (2006).
(41) Click chemistry on curdlan: A regioselective and quantitative approach to develop artificial beta-1,3-Glucans with various functional appendages. T. Hasegawa, M. Umeda, M. Numata, T. Fujisawa, S. Haraguchi, K. Sakurai, S. Shinkai, Chem. Lett., 35, 82 (2006).
2005
(40) Poly(diacetylene) nanofibers can be fabricated through photo-irradiation using natural polysaccharide schizophyllan as a one-dimensional mold. T. Hasegawa, S. Haraguchi, M. Numata, C. Li, A.-H. Bae, T. Fujisawa, K. Kaneko, K. Sakurai, S. Shinkai, Org. Bioorg. Chem., 3, 4321 (2005).
(39) Click chemistry' on polysaccharides: a convenient, general, and monitor approach to develop beta-1,3-D-glucan with various functional appendages. T. Hasegawa, M. Umeda, M. Numata, C. Li, A.-H. Bae, T. Fujisawa, S. Haraguchi, K. Sakurai, S. Shinkai, Carbohydrate Res., 34, 35 (2006).
(38) Oligosilane-nanofibers can be prepared through fabrication of permethyldecasilane within a helical superstructure of schizophyllan. S. Haraguchi, T. Hasegawa, M. Numata, M. Fujiki, K. Uezu, K. Sakurai, S. Shinkai, Org. Lett., 7, 5605 (2005).
(37) Water-soluble poly(3,4-ethylenedioxythiophene) nanoparticles created by a templating effect of beta-1.3-glucan schizophyllan, C. Li, M. Numata, T. Hasegawa, T. Fujisawa, S. Haraguchi, K. Sakurai, and S. Shinkai, Chem. Lett., 34, 1354 (2005).
(36) A sensitive colorimetric and fluorescent probe based on a polythiophene derivative for the detection of ATP, C. Li, M. Numata, M. Takeuchi, and S. Shinkai, Angew, Chem. Int. Ed., 44, 6371 (2005).
(35) Water-soluble polythiophene as an opitical probe for detection of the helicity and conformational transition in polysaccharides, C. Li, M. Numata, T. Hasegawa, K. Sakurai, and S. Shinkai, Chem. Lett., 34, 1354 (2005).
(34) beta-1,3-Glucans polysaccharides as novel one-dimensional hosts for DNA/RNA, conjugated polymers and nanoparticles. K. Sakurai, K. Uezu, M. Numata, T. Hasegawa, C. Li, K. Kaneko, and S. Shinkai, Chem. Commun (Feature Article)., 2005, 4383. [Chem. Commun. Top 10 Articles]
(33) beta-1.3-Glucan polysaccharide can act as a one-dimensional host to create novel silica nanofiber structures, M. Numata, C. Li, A.-H. Bae, K. Kaneko, K. Sakurai, and S. Shinkai, Chem. Commun., 2005, 4655.
(32) Schizophyllan acts as a one-dimensional host to accommodate 5, 10, 15, 20-tetrakis (4-carboxyphenyl)porphyrinatozinc acetate to produce its fibrous superstructure, T. Hasegawa, T. Fujisawa, M. Numata, C. Li, A.-H. Bae, S. Haraguchi, K. Sakurai, and S. Shinkai, Chem. Lett., 34, 1118 (2005).
(31) Transferrin-appended beta-1,3-D-glucan schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake, T. Anada, R. Karinaga, M. Mizu, K. Koumoto, T. Matsumoto, M. Numata, S. Shinkai, and K. Sakurai, e-J. of Surface Science and Nanotechnology, 3, 195 (2005).
(30) Pallalel vs. anti-parallel orientation in a curdlan/oligo(dA) complex as estimated by a FRET technique, M. Numata, K. Koumoto, M. Mizu, K. Sakurai, and S. Shinkai, Organic. Bioorganic. Chem., 3, 2255 (2005).
(29) Inclusion of cut and as-grown single-walled carbon nanotubes in the helical superstructure of schizophyllan and curdlan (beta-1,3-glucans), M. Numata, M. Asai, K. Kaneko, T. Hasegawa, K. Sakurai, and S. Shinkai, J. Am. Chem. Soc., 127, 5875 (2005).
(28) Poly(N-substituted-acrylamide)-branched schizophyllans are useful for selective recovery of homopolynucleotides through convenient and quick precipitation procedures, T. Matsumoto, M. Umeda, T. Hasegawa, M. Numata, K. Sakurai, K. Koumoto, and S. Shinkai, Polymer J., 37, 177 (2005).
(27) Self-assembly of supramolecular chiral insulated molecular wire, C. Li, M. Numata, A.-H. Bae, K. Sakurai, and S. Shinkai, J. Am. Chem. Soc., 127, 4548 (2005).[ACS Most-Accessed Article]
(26) 1D arrangement of Au nanoparticles by the helical structure of schizophyllan: a unique encounter of a natural product with inorganic compounds, A.-H. Bae, M. Numata, T. Hasegawa, C. Li, K. Kaneko, K. Sakurai, and S. Shinkai, Angew. Chem. Int. Ed., 44, 2030 (2005).[Selected as Cover Picture]
(25) Schizophyllan-folate conjugate as a new non-cytotoxic and cancer-targeted antisense carrier, T. Hasegawa, T. Fujisawa, S. Haraguchi, M. Numata, R. Karinaga, T. Kimura, S. Okumura, K. Sakurai, and S. Shinkai, Bioorg. Med. Chem. Lett., 15, 327 (2005).
(24) Schizophyllan can act as a one-dimensional host to construct poly(diacetylene) nanofibers, T. Hasegawa, S. Haraguchi, M. Numata, T. Fujisawa, C. Li, K. Kaneko, K. Sakurai, and S. Shinkai, Chem. Lett., 34, 40 (2005).
(23) Superstructural poly(pyrrole) assemblies created by a DNA templating method, A.-H. Bae, T. Hatano, M. Numata, M. Takeuchi, and S. Shinkai, Macromolecules, 38, 1609 (2005).
2004
(22) Sol-gel reaction using DNA as a template: an attempt toward transcription of DNA into inorganic materials, M. Numata, K. Sugiyasu, T. Hasegawa, and S. Shinkai, Angew. Chem. Int. Ed., 43, 3279 (2004).[WILEY Press Release (Link) ]
(21) beta-1,3-Glucan (schizophyllan) can act as a one-dimensional host for creation of novel poly(aniline) nanofiber structures, M. Numata, T. Hasegawa, T. Fujisawa, K. Sakurai, and S. Shinkai, Org. Lett., 6, 4447 (2004).
(20) Complementary hydrogen-bonding between tymidine-based low molecular-weight gelator and polynucleotide in organic media, K. Sugiyasu, M. Numata, N. Fujita, S.-M. Park, Y.-J. Yun, B.-H. Kim, and S. Shinkai, Chem. Commun., 2004, 1996 .
(19) Higher-order conformations of DNA are useful as templates to create various superstructural poly(pyrrole) morphologies, A.-H. Bae, T. Hatano, M. Numata, M. Takeuchi, and S. Shinkai, Chem. Lett., 33, 436 (2004).
(18) Schizophyllans carrying oligosaccharide appendages as potential candidates for cell-targeted antisense carrier, T. Hasegawa, T. Fujisawa, M. Numata, T. Matsumoto, M. Umeda, R. Karinaga , M. Mizu, K. Koumoto, T. Kimura, S. Okumura, K. Sakurai, and S. Shinkai, Org. Biomol. Chem., 2, 3091 (2004).
(17) Single-walled carbon nanotubes acquire a specific lectin-affinity through supramolecular wrapping with lactose-appended schizophyllan, T. Hasegawa, T. Fujisawa, M. Numata, M. Umeda, T. Matsumoto, T. Kimura, S. Okumura, K. Sakurai, and S. Shinkai, Chem. Commun., 2004, 2150
(16) A polysaccharide carrier for immunostimulatory CpG DNAs to enhance cytokine secretion, M. Mizu, K. Koumoto, T. Anada, T. Matsumoto, M. Numata, S. Shinkai, T. Nagasaki, and K. Sakurai, J. Am. Chem. Soc., 126, 8372 (2004).
(15) Curdlan and schizophyllan (beta-1,3-glucans) can entrap single-wall carbon nanotubes in their helical superstructure, M. Numata, M. Asai, K. Kaneko, T. Hasegawa, N. Fujita, Y. Kitada, K. Sakurai, and S. Shinkai, Chem. Lett., 33, 232 (2004).
(14) Lactose-appended schizophyllan is a potential candidate as a hepatocyte-targeted antisense carrier, T. Hasegawa, M. Umeda, T. Matsumoto, M. Numata, M. Mizu, K. Koumoto, K. Sakurai, and S. Shinkai, Chem. Commun., 2004, 382.
(13) Chemically modified polysaccharide schizophyllan for antisense oligonucleotides delivery to enhance the cellular uptake efficiency, T. Matsumoto, M. Numata, M. Mizu, K. Koumoto, T. Anada, K. Sakurai, T. Nagasaki, and S. Shinkai, Biochimica et Biophysica Acta-General Subjects, 1670, 91 (2004).
(12) Low Mw sulfated curdlan with improved water solubility forms macromolecular complexes with polycytidylic acid, K. Koumoto, M. Umeda, M. Numata, T. Matsumoto, K. Sakurai, T. Kunitake, and S. Shinkai, Carbohydr. Res., 339, 161 (2004).
2003
(11) Polysaccharide-polynucleotide complexes (15): thermal stability of schizophyllan (SPG)/Poly(C) triple strands is controllable by ｱ-amino acid modification, M. Numata, T. Matsumoto, M. Umeda, K. Koumoto, K. Sakurai, T. Kunitake, and S. Shinkai, Bioorg. Chem., 31, 163 (2003).
(10) Polynucleotide can stabilize nucleobase-appended cholesterol gels,
M. Numata and S. Shinkai, Chem. Lett., 32, 308 (2003).
2002
(9) A new synthetic method for rotaxanes via tandem Claisen rearrangement, diesterification, and aminolysis, K. Hiratani, J. Suga, Y. Nagawa, H. Houjou, H. Tokuhisa, M. Numata, K. Watanabe, Tetrahedron Lett., 43, 5747 (2002).
(8) Efficient synthesis of novel macrocyclic tetraamide compounds: a unique reaction process involving both self-assembling and folding of intermediates, M. Numata, K. Hiratani, Y. Nagawa, H. Houjou, S. Masubuchi, S. Akabori, New, J. Chem., 26, 503 (2002).
2000
(7) Thermodynamic insight into the origin of a calyx[n]arene-[60]fullerene interaction and its application to a porphyrin-[60]fullerene energy transfer system, A. Ikeda, M. Kawaguchi, Y. Suzuki, T. Hatano, M. Numata, S. Shinkai, A. Ohta, M. Aratono, J. Inclusion Phenomena and Macrocyclic Chemistry, 38, 163 (2000).
(6) Polybenzyl ether dendrimers for the complexation of [60]fullerenes, J.-F. Eckert, D. Byrne, J.-F. Nicoud, L. Oswald, J.-F. Nierengarten, M. Numata, A. Ikeda, S. Shinkai, N. Armaroli, New. J. Chem., 24, 749 (2000).
(5) Properly assembled dendrons can be immobilized into dendrimers by in situ crosslink, M. Numata, A. Ikeda, S. Shinkai, Chem. Lett., 2000, 370.
(4) Three-to-sic-carbon ring-enlargement reaction of cyclic ortho esters bearing a diazocarbonyl side chain, Use of the intermolecular formation of tricyclooxonium ylides, A. Oku, M. Numata, J. Org. Chem., 65, 1899 (2000).
(3) Pyridine-appended 5,6-open-aza[60]fulleroid can act as a unique host for alcohols, A. Ikeda, C. Fukuhara, M. Kawaguchi, M. Numata, S. Shinkai, S.-G. Liu, L. Echegoyen, J. Chem. Soc., Perkin 2, 2000, 307.
1999
(2) A novel attempt to control the aggregation number of dendrons with a saccharide, A. Ikeda, M. Numata, S. Shinkai, Chem., Lett., 1999, 929.
(1) Dendrimers can act as a host for [60]fullerene, M. Numata, A. Ikeda, C. Fukuhara, S. Shinkai, Tetrahedron Lett., 40, 6945 (1999).

Books and Reviews:
(1) "b-1,3-Glucans polysaccharides as novel one-dimensional hosts for DNA/RNA, conjugated polymers and nanoparticles", K. Sakurai, K. Uezu, M. Numata, T. Hasegawa, C. Li, K. Kaneko, and S. Shinkai, Chem. Commun. (Feature Article), 4383-4398 (2005).(→Link)
(2)“核酸をテンプレートとする１次元集積体とナノ化石-分子認識と構造転写を利用した有機および無機ハイブリッドの創製”沼田宗典、新海征治、化学と工業　2005年、５月号、 vol. 58、pp.586-588.
(3)”多糖β１、３グルカンを１次元ホストとして用いたバイオナノマテリアルの創製”日本化学会　生体機能関連化学部会、News Letter、vol. 20, No. 3, pp. 10-13 (2005).
(4)“モレキュラーインフォーマティクスを拓く分子機能材料（新海征治　編著）日刊工業新聞社、pp16-18(2006)（分筆）
(5) "Molecular assemblies as templates toward the creation of functional superstructures"
M. Takeuchi, M. Numata, N. Fujita, K. Sada, and S. Shinkai, Chem. Soc. Rev., 36, 415 (2007). (→Link)
(6)”高分子にアシストされる超分子形成”-光機能材料を指向した超分子色素系の創製を目指して-沼田宗典、民秋均、化学、2007年、vol. 62、No. 9、pp.70-71.
(7)「有機・無機・金属ナノチューブ」-非カーボンナノチューブ系の最新技術と応用展開-　清水敏美、木島　剛　編集、第４章　高分子系ナノチューブ ”β-1,3-グルカン系多糖高分子を用いた一次元シリンダーホスト”沼田宗典、新海征治、フロンティア出版、2008年３月　（→リンク）
(8) "Self-Assembled Polysaccharide Nanotubes Generated from beta-1,3-Glucan Polysaccharides", Munenori Numata and Seiji Shinkai, Advances in Polymer Science, ed. by T. Shimizu, Springer, Berlin, June, 28, 2008, Published Online.　（→ Link)
(9)超分子サイエンスー基礎から材料への展開ー（国武豊喜　監修）第２章　１次元分子集合体
　"ゲスト誘導型多糖系ホストの新展開"　沼田宗典、　エス・ティー・エス出版 (2009)　印刷中

新聞発表:

　　　　日刊工業新聞、２００４年、６月２５日（朝刊）

　　（２）“世界初ナノ配線-キノコの多糖を活用、電化製品や医療応用-”

　　　　読売新聞、２００５年、３月１０日（朝刊）
　　（３）“ナノチューブに糖を巻き付け-九大配線などに応用-”

　　　　日本経済新聞、２００５年、１２月９日（朝刊）

　　　受賞:

生体機能関連化学部会　部会講演賞（第２０回　生体機能関連化学シンポジウム、名古屋市立大）“多糖・β１、３グルカンを１次元ホストとした新規ナノコンポジット群の創製”
第２２回若い世代の特別講演証（日本化学会第８８回春期年会、立教大学）”らせん状多糖高分子のラッピング機能を利用したナノマテリアルの創製”

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